J Pediatr. 2004 Jan.
Sudden death in growth hormone-treated children with Prader-Willi syndrome.
Van Vliet G, Deal CL, Crock PA, Robitaille Y, Oligny LL. Departments of Pediatrics and Pathology, Sainte-Justine Hospital and Research Center, University of Montreal, Quebec, Canada.
[ PubMed ]

Abstract: A 4-year-old boy with Prader-Willi syndrome died suddenly while asleep on day 67 of growth hormone treatment. During treatment, snoring had worsened. Autopsy showed multifocal bronchopneumonia. This case and two others recently published suggest that growth hormone may be associated with obstructive apnea, respiratory infection, and sudden death in this condition.