Eur Child Adolesc Psychiatry. 1998 Sep.
Is monoamine oxidase activity elevated in Prader-Willi syndrome?
Akefeldt A, Mansson JE.
Department of Child and Adolescent Psychiatry, Goteborg University, Annedals Clinics, Sweden.
[ PubMed ]

Abstract: The platelet contents of monoamine oxidase (MAO-B) were analyzed in 17 children and young adults with Prader-Willi syndrome and 18 non-PWS comparison cases. MAO-B activity was significantly higher in the former group, suggesting monoamine dysfunction in Prader-Willi syndrome.

[Note: MOA-B is an enzyme that catalyzes the inactivation or breakdown of monoamines such as the neurotransmitter dopamine and phenethylamines.]